5,6-Dihydroxyindole

5,6-Dihydroxyindole, a melanin precursor, has a broad-spectrum antibacterial, antifungal, antiviral, antiparasitic activity. 5,6-Dihydroxyindole has cytotoxic effects and is strongly toxic against various pathogens[1].

Product Specifications

CAS Number

[3131-52-0]

UNSPSC

12352005

Hazard Statement

H302, H318, H411

Target

Bacterial; Endogenous Metabolite; Fungal; Parasite

Type

Natural Products

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Applications

COVID-19-anti-virus

Field of Research

Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/5-6-dihydroxyindole.html

Purity

99.77

Solubility

DMSO : 100 mg/mL|H2O : < 0.1 mg/mL (ultrasonic)

Smiles

OC1=CC2=C(C=C1O)C=CN2

Molecular Formula

C8H7NO2

Molecular Weight

149.15

Precautions

H302, H318, H411

References & Citations

[1]Zhao P, et al. Antiviral, anti-parasitic, and cytotoxic effects of 5,6-dihydroxyindole (DHI), a reactive compound generated by phenoloxidase during insect immune response. Insect Biochem Mol Biol. 2011 Sep;41 (9) :645-52.|[2]Heiduschka P, et al. Melanin precursor 5,6-dihydroxyindol: protective effects and cytotoxicity on retinal cells in vitroand in vivo. Toxicol Pathol. 2007 Dec;35 (7) :1030-8.