β-Pompilidotoxin

β-Pompilidotoxin (β-PMTX), a wasp venom, can slow sodium channel inactivation and increases steady-state sodium current in cells[1].

Product Specifications

CAS Number

216064-36-7

Product Name Alternative

β-PMTX

UNSPSC

12352209

Target

Sodium Channel

Type

Peptides

Related Pathways

Membrane Transporter/Ion Channel

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/β-pompilidotoxin.html

Purity

97.12

Solubility

H2O : ≥ 100 mg/mL

Smiles

[C@H](CC1=CC=CC=C1)(C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC(C)C)C(N)=O)=O)CCCNC(=N)N)=O)CO)=O)CC(C)C)=O)CCC(N)=O)=O)CC(O)=O)=O)NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CCCNC(=N)N)N)=O)[C@H](CC)C)=O)CCCCN)=O)[C@H](CC)C)=O)=O)CC(C)C)=O

Molecular Formula

C71H124N22O17

Molecular Weight

1557.88

References & Citations

[1]Tina M Grieco, et al. Production of resurgent current in NaV1.6-null Purkinje neurons by slowing sodium channel inactivation with beta-pompilidotoxin. J Neurosci. 2004 Jan 7;24 (1) :35-42.