ATG4C Recombinant Rabbit Monoclonal Antibody [JE59-99]
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding the same protein, have been characterized.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
ATG4C, APG4C, AUTL1, AUTL3
Swiss Prot
Q96DT6 Human, Q811C2 Mouse
Cellular Locus
Cytoplasm.
Host
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Recombinant protein within Human ATG4C aa 309-458 / 458.
Isotype
IgG
Clone
JE59-99
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IF-Cell, IHC-P, FC
Positive Control
HeLa cell lysate, Jurkat cell lysate, Raji cell lysate, HEK-293 cell lysate, Jurkat, HeLa, human testis tissue, mouse skeletal muscle tissue.
Concentration
1 mg/mL
Dilution
WB: 1:1,000 ;IF-Cell: 1:100 ;IHC-P: 1:1,000 ;FC: 1:1,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 52 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
Frequently Asked Questions
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