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CDKN2A Polyclonal Antibody

Product Specifications

Background

Acts as a negative regulator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6. This inhibits their ability to interact with cyclins D and to phosphorylate the retinoblastoma protein.

Abbreviation

CDKN2A

UniProt

P42771

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant Human CDKN2A protein expressed by E.coli

Target

CCM2; CDK4 inhibitor p16 INK4; Cell cycle negative regulator beta; Cyclin dependent kinase 4 inhibitor A; Cyclin Dependent Kinase Inhibitor 2A; Cyclin dependent kinase inhibitor 2A (melanoma p16 inhibits CDK4) ; Cyclin dependent kinase inhibitor 2A isoform 4; Cyclin dependent kinase inhibitor 2A isoforms 1/2/3; Cyclin dependent kinase inhibitor p16; Multiple tumor suppressor 1; INK; CMM; CDKN; P16INK; MTS; CDKN2A; ARF; CDK4I; CDKN2; CMM2; INK4; INK4A; MLM; MTS-1; MTS1; P14; P14ARF; P16; P16-INK4A; P16INK4; P16INK4A; P19; P19ARF; TP16; Cyclin-dependent kinase inhibitor 2A

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Cell Biology; Epigenetics and Nuclear Signaling; Cancer

Purification

Antigen Affinity Purification

Concentration

1 mg/mL

Dilution

WB 1:500-1:1000; IHC 1:400-1:800

Buffer

PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. Protected from prolonged exposure to light.

Product Datasheet

https://789.bio/ea/dhlxlc

Product MSDS

https://789.bio/eb/dHOC0C

Calculated Molecular Weight

14 kDa

Observed Molecular Weight

16 kDa

Isotype

IgG

Available Sizes

Curated Selection

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