Dimemorfan (phosphate)

Dimemorfan phosphate is a sigma 1 receptor agonist, used as a potent antitussive.

Product Specifications

CAS Number

[36304-84-4]

UNSPSC

12352005

Target

Sigma Receptor

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/Dimemorfan_phosphate.html

Purity

99.94

Solubility

DMSO : 1 mg/mL (ultrasonic) |H2O : 10 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=P(O)(O)O.CN1[C@](CC2=CC=C(C)C=C32)([H])[C@](CCCC4)([H])[C@]34CC1

Molecular Formula

C18H28NO4P

Molecular Weight

353.39

References & Citations

[1]Shin EJ, et al. Dimemorfan prevents seizures induced by the L-type calcium channel activator BAY k-8644 in mice. Behav Brain Res. 2004 May 5;151 (1-2) :267-76.|[2]Wang YH, et al. Anti-inflammatory effects of dimemorfan on inflammatory cells and LPS-induced endotoxin shock in mice. Br J Pharmacol. 2008 Jul;154 (6) :1327-38.