Rubioncolin C
Rubioncolin C exerts anti-tumor activity by inducing apoptotic and autophagic Cell Death and inhibiting the NF-κB and Akt/mTOR/P70S6K Pathway in Human Cancer Cells[1].
Product Specifications
CAS Number
132242-52-5
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
NF-κB
Type
Natural Products
Related Pathways
NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/rubioncolin-c.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=C(C/C=C(C)\C)C(OC(C2=O)=CC(C3=C2C=CC=C3)=O)=C4C=CC=CC4=C1O)OC
Molecular Formula
C27H22O6
Molecular Weight
442.46
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Wang J, et al. Natural Naphthohydroquinone Dimer Rubioncolin C Exerts Anti-Tumor Activity by Inducing Apoptotic and Autophagic Cell Death and Inhibiting the NF-κB and Akt/mTOR/P70S6K Pathway in Human Cancer Cells. Cells. 2019;8 (12) :1593. Published 2019 De
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
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