Rubioncolin C

Rubioncolin C exerts anti-tumor activity by inducing apoptotic and autophagic Cell Death and inhibiting the NF-κB and Akt/mTOR/P70S6K Pathway in Human Cancer Cells[1].

Product Specifications

CAS Number

[132242-52-5]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

NF-κB

Type

Natural Products

Related Pathways

NF-κB

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/rubioncolin-c.html

Solubility

10 mM in DMSO

Smiles

O=C(C1=C(C/C=C(C)\C)C(OC(C2=O)=CC(C3=C2C=CC=C3)=O)=C4C=CC=CC4=C1O)OC

Molecular Formula

C27H22O6

Molecular Weight

442.46

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Wang J, et al. Natural Naphthohydroquinone Dimer Rubioncolin C Exerts Anti-Tumor Activity by Inducing Apoptotic and Autophagic Cell Death and Inhibiting the NF-κB and Akt/mTOR/P70S6K Pathway in Human Cancer Cells. Cells. 2019;8 (12) :1593. Published 2019 De