MK-3402
MK-3402 (Compound303) is a metallo-beta-lactamase inhibitor, with IC50 values of 0.53, 0.25 and 0.169 nM against IMP-1, NDM-1, and VIM-1, respectively. MK-3402 can be used in bacterial research and shows a synergistic effect when used in combination with beta-lactam antibiotics[1].
Product Specifications
CAS Number
[2058151-78-1]
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/mk-3402.html
Purity
99.96
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 80°C)
Smiles
NS(=O)(C1=C(C2=NN=NN2)C(C3=CN=C(N)C=C3)=CC=C1S(NC[C@H](O)CN)(=O)=O)=O
Molecular Formula
C15H19N9O5S2
Molecular Weight
469.50
References & Citations
[1]Frank Bennett, et al. 3-tetrazolyl-benzene-1,2-disulfonamide derivatives as metallo-beta-lactamase inhibitors. Patent. WO2016210215.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 1
Available Sizes
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