LCKLSL (hydrochloride)
Product Specifications
UNSPSC Description
LCKLSL hydrochloride is a N-terminal hexapeptide and a competitive annexin A2 (AnxA2) inhibitor. LCKLSL hydrochloride potently inhibits the binding of tissue plasminogen activator (tPA) to AnxA2. LCKLSL hydrochloride also inhibits the generation of plasmin and has anti-angiogenic roles[1].
Target Antigen
Annexin A
Type
Peptides
Related Pathways
Cytoskeleton
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/lcklsl-hydrochloride.html
Purity
99.76
Solubility
DMSO : 25 mg/mL (ultrasonic)|H2O : 10 mg/mL (ultrasonic)
Smiles
CC(C)C[C@@H](C(O)=O)NC([C@H](CO)NC([C@H](CC(C)C)NC([C@H](CCCCN)NC([C@H](CS)NC([C@H](CC(C)C)N)=O)=O)=O)=O)=O.Cl
Molecular Weight
712.34
References & Citations
[1]Mallika Valapala, et al. A Competitive Hexapeptide Inhibitor of Annexin A2 Prevents Hypoxia-Induced Angiogenic Events. J Cell Sci. 2011 May 1;124(Pt 9):1453-64.J Extracell Vesicles. 2024 Apr;13(4):e12425.|J Neurochem. 2022 Mar;160(6):662-674.|Biomed Pharmacother. 2023 Mar;159:114173.|Inflamm Res. 2022 Jul 28.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P2333A/LCKLSL-hydrochloride-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P2333A/LCKLSL-hydrochloride-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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