DSP-2230
Product Specifications
UNSPSC Description
DSP-2230 is a selective Nav1.7/Nav1.8 blocker, can be used to improve neuropathic pain[1][2][3].
Target Antigen
Sodium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Field of Research
Neurological Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/dsp-2230.html
Purity
98.33
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
C[C@H](NCC1=NC2=CC=C(OC3=CC(F)=C(F)C(F)=C3)N=C2N1C4CCC4)C(N)=O
Molecular Weight
419.40
References & Citations
[1]Bagal SK, et al. Voltage gated sodium channels as drug discovery targets. Channels (Austin). 2015;9(6):360-6.|[2]Sara Sabina Hadida-Ruah, et al. Sulfonamides as modulators of sodium channels.|[3]Matthew Alsaloum, et al. Status of peripheral sodium channel blockers for non-addictive pain treatment. Nat Rev Neurol. 2020 Dec;16(12):689-705.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-125079/DSP-2230-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-125079/DSP-2230-SDS-MedChemExpress.pdf
Clinical Information
Phase 1
CAS Number
1233231-30-5
Available Sizes
Curated Selection
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