Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Incadronic acid

Incadronic acid inhibits growth of Dictyostelium discoideum with an IC50 of 1.6 μM. Incadronic acid binds the farnesyl diphosphate synthase (FPPS) in Leishmania major with the Ki of 23 nM. Incadronic acid inhibits the bone resorption and reduces bone loss, that can be used in osteoporosis research. Incadronic acid inhibits the proliferation of cells RAW264.7, PC-3 and MCF-7 with IC50 of 48 to 228.6 µM[1].

Product Specifications

CAS Number

124351-85-5

UNSPSC

12352211

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Cancer; Infection; Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/incadronic-acid.html

Purity

98.03

Solubility

DMSO : 12.5 mg/mL (ultrasonic)

Smiles

O=P(O)(C(P(O)(O)=O)NC1CCCCCC1)O

Molecular Formula

C8H19NO6P2

Molecular Weight

287.19

References & Citations

[1]Petruczynik P, et al., Three-Component Reaction of Diamines with Triethyl Orthoformate and Diethyl Phosphite and Anti-Proliferative and Antiosteoporotic Activities of the Products. Molecules. 2020 Mar 20;25 (6) :1424.|[2]Bisphosphonate compounds and methods for bone resorption diseases, cancer, bone pain, immune disorders, and infectious diseases. WO2006039721.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

AK6 Rabbit Polyclonal Antibody
R1406-1 100 µL

AK6 Rabbit Polyclonal Antibody

Sign In for Pricing
View Details
Mouse Fli1 activation kit by CRISPRa
GA201443 1 Kit

Mouse Fli1 activation kit by CRISPRa

Sign In for Pricing
View Details
C15orf32 Human Gene Knockout Kit (CRISPR)
KN418523 1 Kit

C15orf32 Human Gene Knockout Kit (CRISPR)

Sign In for Pricing
View Details
S100B (4C4.9), CF647 conjugate, 0.1mg/mL
BNC470143-500 1x 500 µL

S100B (4C4.9), CF647 conjugate, 0.1mg/mL

Sign In for Pricing
View Details
Sumo 1 (SUMO1) Mouse Monoclonal Antibody [Clone ID: 5B12]
AM26638AF-N 100 µg

Sumo 1 (SUMO1) Mouse Monoclonal Antibody [Clone ID: 5B12]

Sign In for Pricing
View Details
2-Chloro-4-piperidinopyrimidine
TRC-C350900-50MG 50 mg

2-Chloro-4-piperidinopyrimidine

Sign In for Pricing
View Details