ERX-41
ERX-41 is an orally active and stereospecific small molecule targeting to lysosomal acid lipase A (LIPA) . ERX-41 induces endoplasmic reticulum (ER) stress resulting in cell death, indicating a function independent of LIPA but dependent on its ER localization. ERX-41 involves in a targeted strategy for solid tumors[1].
Product Specifications
CAS Number
[2440087-54-5]
UNSPSC
12352005
Target
Lipase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/erx-41.html
Purity
98.25
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
O=C(C1=CC(OCCO)=C(C=C1)[N+]([O-])=O)NC2=C(C=C(C=C2)C(NC3=C(C=C(C=C3)C(N[C@H]4CC[C@@H](CC4)C)=O)OCC(C)C)=O)OCC(C)C
Molecular Formula
C38H48N4O9
Molecular Weight
704.81
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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Phosphoinositide 3 Kinase, p110 alpha (PI3K, caPI3K, MGC142161, MGC142163, p110 alpha, p110-alpha, Phosphatidylinositol 3 Kinase Catalytic alpha Polypeptide, Phosphatidylinositol 3 Kinase Catalytic 110kD alpha, Phosphatidylinositol-4,5-bisphosphate 3-kina
Phosphoinositide 3 Kinase, p110 alpha (PI3K, caPI3K, MGC142161, MGC142163, p110 alpha, p110-alpha, Phosphatidylinositol 3 Kinase Catalytic alpha Polypeptide, Phosphatidylinositol 3 Kinase Catalytic 110kD alpha, Phosphatidylinositol-4,5-bisphosphate 3-kina