2,4-Diamino-6-hydroxypyrimidine
2,4-Diamino-6-hydroxypyrimidine is a specific GTP cyclohydrolase I inhibitor (the rate-limiting enzyme in de novo pterin synthesis) . 2,4-Diamino-6-hydroxypyrimidine blocks Tetrahydrobiopterin (BH4) synthesis and suppresses NO production[1][2].
Product Specifications
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
NO Synthase
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/2-4-diamino-6-hydroxypyrimidine.html
Purity
99.97
Solubility
DMSO : 16.67 mg/mL (ultrasonic) |H2O : 10 mg/mL (ultrasonic)
Smiles
O=C1N=C(N)NC(N)=C1
Molecular Formula
C4H6N4O
Molecular Weight
126.12
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-100954/2-4-Diamino-6-hydroxypyrimidine-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-100954/2-4-Diamino-6-hydroxypyrimidine-SDS-MedChemExpress.pdf
Scientific Category
Reference compound1
Clinical Information
No Development Reported
CAS Number
[56-06-4]
Available Sizes
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