EMT inhibitor-1
EMT inhibitor-1 is an inhibitor of of Hippo, TGF-β, and Wnt signaling pathways with antitumor activities.
Product Specifications
CAS Number
[1638526-21-2]
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
Hippo (MST) ; TGF-beta/Smad; Wnt
Type
Reference compound
Related Pathways
Stem Cell/Wnt; TGF-beta/Smad
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/EMT_inhibitor-1.html
Purity
99.45
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OCCCCOC1=NSN=C1C2=CC=C(Cl)C(Cl)=C2
Molecular Formula
C12H12Cl2N2O2S
Molecular Weight
319.21
Precautions
H302, H315, H319
References & Citations
[1]Basu D, et al. Identification, mechanism of action, and antitumor activity of a small molecule inhibitor of hippo, TGF-β, and Wnt signaling pathways. Mol Cancer Ther. 2014 Jun;13 (6) :1457-67.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 1
Available Sizes
Curated Selection
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