IONIS PTP1BRx
IONIS PTP1BRx (ISIS 404173) is an antisense inhibitor of protein tyrosine phosphatase 1B (PTP-1B) . IONIS PTP1BRx shows antidiabetic activity, and can be used for the study of insulin resistance and type 2 diabetes mellitus associated with obesity[1].
Product Specifications
CAS Number
1403406-29-0
Product Name Alternative
ISIS 404173
UNSPSC
12352208
Target
Phosphatase
Type
Oligonucleotides
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/ionis-ptp1brx.html
Smiles
[IONISPTP1BRx]
References & Citations
[1]Stanley T Crooke, et al. The Effects of 2'-O-Methoxyethyl Oligonucleotides on Renal Function in Humans. Nucleic Acid Ther. 2018 Feb;28 (1) :10-22.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
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