Cyclocurcumin
Cyclocurcumin is a potent p38α inhibitor. Cyclocurcumin shows antirheumatic, antivasoconstrictive and antioxidant activities[1][2][3].
Product Specifications
CAS Number
[153127-42-5]
UNSPSC
12352005
Target
P38 MAPK
Type
Natural Products
Related Pathways
MAPK/ERK Pathway
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/cyclocurcumin.html
Purity
99.48
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1CC(C(C=C2)=CC(OC)=C2O)OC(/C=C/C(C=C3)=CC(OC)=C3O)=C1
Molecular Formula
C21H20O6
Molecular Weight
368.38
References & Citations
[1]Fu M, et al. Cyclocurcumin, a curcumin derivative, exhibits immune-modulating ability and is a potential compound for the treatment of rheumatoid arthritis as predicted by the MM-PBSA method. Int J Mol Med. 2017 May;39 (5) :1164-1172.|[2]Kim K, et al. Cyclocurcumin, an Antivasoconstrictive Constituent of Curcuma longa (Turmeric) . J Nat Prod. 2017 Jan 27;80 (1) :196-200.|[3]Li Y, et al. Antioxidant properties and free radical scavenging mechanisms of cyclocurcumin. New Journal of Chemistry, 2018, 42 (15) : 12698-12705.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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