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Cyclocurcumin

Cyclocurcumin is a potent p38α inhibitor. Cyclocurcumin shows antirheumatic, antivasoconstrictive and antioxidant activities[1][2][3].

Product Specifications

CAS Number

153127-42-5

UNSPSC

12352005

Target

P38 MAPK

Type

Natural Products

Related Pathways

MAPK/ERK Pathway

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/cyclocurcumin.html

Purity

99.48

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C1CC(C(C=C2)=CC(OC)=C2O)OC(/C=C/C(C=C3)=CC(OC)=C3O)=C1

Molecular Formula

C21H20O6

Molecular Weight

368.38

References & Citations

[1]Fu M, et al. Cyclocurcumin, a curcumin derivative, exhibits immune-modulating ability and is a potential compound for the treatment of rheumatoid arthritis as predicted by the MM-PBSA method. Int J Mol Med. 2017 May;39 (5) :1164-1172.|[2]Kim K, et al. Cyclocurcumin, an Antivasoconstrictive Constituent of Curcuma longa (Turmeric) . J Nat Prod. 2017 Jan 27;80 (1) :196-200.|[3]Li Y, et al. Antioxidant properties and free radical scavenging mechanisms of cyclocurcumin. New Journal of Chemistry, 2018, 42 (15) : 12698-12705.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Natural Products

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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