Nicosulfuron

Nicosulfuron is efficient, harmless, antifungal and selective herbicide belonging to the sulfonylurea family. Nicosulfuron is also a photosynthetic system inhibitor and inhibits acetolactate synthase (ALS) enzyme activity. Nicosulfuron degradation by Plectosphaerella cucumerina AR1 is glucose concentration dependent in planktonic lifestyle. Nicosulfuron enhances the glycolysis pathway and tricarboxylic acid cycle to improve the adaptability of sweet maize. Nicosulfuron reduces the synthesis of branched-chain amino acids (BCAAs), which is proming for maize cultivation[1][2][3][4].

Product Specifications

CAS Number

[111991-09-4]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Acetolactate Synthase (ALS) ; Fungal; Photosystem II

Type

Reference compound

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/nicosulfuron.html

Concentration

10mM

Purity

97.15

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C(C1=CC=CN=C1S(=O)(NC(NC2=NC(OC)=CC(OC)=N2)=O)=O)N(C)C

Molecular Formula

C15H18N6O6S

Molecular Weight

410.41

Precautions

H302, H315, H319, H335

References & Citations

[1]Louis Carles, et al. Nicosulfuron Degradation by an Ascomycete Fungus Isolated From Submerged Alnus Leaf Litter. Front Microbiol. 2018 Dec 19;9:3167.|[2]Xu N, et al. Effects of nicosulfuron on plant growth and sugar metabolism in sweet maize (Zea mays L.) [J]. PLoS One. 2022 Oct 21;17 (10) :e0276606.|[3]Zhong J, et al. Current insights into the microbial degradation of nicosulfuron: Strains, metabolic pathways, and molecular mechanisms[J]. Chemosphere. 2023 Jun;326:138390. |[4]Wang J, et al. Adaptation responses in C4 photosynthesis of sweet maize (Zea mays L.) exposed to nicosulfuron[J]. Ecotoxicol Environ Saf. 2021 May;214:112096.