Laurdan

Laurdan is a membrane-permeable fluorescent probe that displays spectral sensitivity to the phospholipid phase of the cell membrane to which it is bound. Quantitation of generalized polarization (GP) of Laurdan can be used to identify phospholipid phase (Ex/Em = 370/440-490 nm) .

Product Specifications

CAS Number

[74515-25-6]

UNSPSC

12171500

Hazard Statement

H302, H315, H319, H335

Target

Fluorescent Dye

Type

Dye Reagents

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/laurdan.html

Purity

99.79

Solubility

DMSO : 5 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

CCCCCCCCCCCC(C1=CC=C2C=C(N(C)C)C=CC2=C1)=O

Molecular Formula

C24H35NO

Molecular Weight

353.54

Precautions

H302, H315, H319, H335

References & Citations

[1]Golfetto O, et al. Laurdan fluorescence lifetime discriminates cholesterol content from changes in fluidity in living cell membranes. Biophys J. 2013 Mar 19;104 (6) :1238-47.