LT25

LT25 (compound 17) is a agonist of α5β1 integrin with EC50 value of 9.9 nM[1].

Product Specifications

CAS Number

[2023788-40-9]

UNSPSC

12352005

Target

Integrin

Type

Reference compound

Related Pathways

Cytoskeleton

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/lt25.html

Concentration

10mM

Purity

98.73

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(CNC(CC1N(C(C1)=O)C(NC2=C(C)C=CC=C2)=O)=O)O

Molecular Formula

C15H17N3O5

Molecular Weight

319.31

References & Citations

[1]Monica Baiula, et al. New β-Lactam Derivatives Modulate Cell Adhesion and Signaling Mediated by RGD-Binding and Leukocyte Integrins. J Med Chem. 2016 Nov 10;59 (21) :9721-9742.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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