Ditekiren
Ditekiren (U 71038) is a pseudohexapeptide renin inhibitor. Renin is an enzyme that plays a crucial role in regulating blood pressure and fluid balance. By inhibiting the activity of renin, ditekiren slows down the formation of angiotensin II, a potent vasoconstrictor that can raise blood pressure. Ditekiren can be used for research in the field of blood pressure reduction[1].
Product Specifications
CAS Number
103336-05-6
Product Name Alternative
U 71038
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Renin
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/ditekiren.html
Smiles
O=C(NCC1=CC=CC=N1)[C@H]([C@@H](C)CC)NC([C@H](C(C)C)C[C@H](O)[C@H](CC(C)C)NC([C@H](CC2=CN=CN2)N(C)C([C@H](CC3=CC=CC=C3)NC([C@H]4N(CCC4)C(OC(C)(C)C)=O)=O)=O)=O)=O
Molecular Formula
C50H75N9O8
Molecular Weight
930.19
Precautions
P261-P280-P302+P352
References & Citations
[1]Adedoyin A, et al. Hepatic elimination in the rat of ditekiren (U-71038), a renin inhibitor pseudohexapeptide[J]. Drug metabolism and disposition, 1993, 21 (1) : 184-188.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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