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Purified Anti-Human CD66b Antibody[G10F5]

Product Specifications

Background

Carcinoembryonic Antigen-Related Cell Adhesion Molecule 8 (CEACAM8) is a single chain, GPI-anchored, highly glycosylated protein which belongs to the immunoglobulin superfamily and the carcinoembryonic antigen (CEA) family. CEACAM8 is expressed by neutrophils and eosinophils, and serves as a binding partner for CEACAM-6 and Galectin-3. It contains two Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. Mature human CEACAM8 is a 287 amino acid GPI-linked glycoprotein. CEACAM family members are a set of widely expressed proteins involved in several biological functions, including cell adhesion, migRation, signal transduction, and the regulation of gene expression. Abnormal overexpression and downregulation of some CEACAMs have been described in tumor cells.

Abbreviation

CD66b

Gene ID

1088

UniProt

P31997

Host

Mouse

Reactivity

Human

Immunogen

Recombinant Human CD66b protein

Target

CGM; NCA; Carcinoembryonic Antigen CGM; Non-Specific Cross-Reacting Antigen NCA; CEACAM; CEACAM8; CD66b; CD67; CGM6; NCA-95; Carcinoembryonic Antigen CGM6; Carcinoembryonic antigen-related cell adhesion molecule 8; CD67 Antigen; Non-Specific Cross-Reacting Antigen NCA-95; CGM6; NCA-95; Carcinoembryonic antigen gene family member 6; Carcinoembryonic antigen related cell adhesion molecule 8; CD 66b; CD 67; CD66b antigen; CEACAM 8; CEAM8; CGM 6; NCA 95; NCA95; Nonspecific cross reacting antigen NCA 95; Nonspecific cross reacting antigen NCA95

Clonality

Monoclonal

Clone

G10F5

Conjugation

Unconjugated

Applications

FCM

Field of Research

Immunology

Purification

>98%, Protein A/G purified

Concentration

≥ 1 mg/mL

Dilution

66

Buffer

Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.

Shipping Conditions

Ice bag

Storage Conditions

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Isotype

Mouse IgM, κ

Available Sizes

Curated Selection

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