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Ac-CoA Synthase Inhibitor1

Ac-CoA Synthase Inhibitor1 is a potent, reversible acetate-dependent acetyl-CoA synthetase 2 (ACSS2) inhibitor with an IC50 of 0.6 μM[1]. Ac-CoA Synthase Inhibitor1 inhibits the respiratory syncytial virus (RSV) [2].

Product Specifications

CAS Number

508186-14-9

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

RSV

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection; Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/Ac-CoA_Synthase_Inhibitor1.html

Purity

99.70

Solubility

DMSO : 31.25 mg/mL (ultrasonic)

Smiles

O=C(NCCOC)NC1=CC=C2N=C(C3=CC=CS3)C(C4=CC=CS4)=NC2=C1

Molecular Formula

C20H18N4O2S2

Molecular Weight

410.51

Precautions

H302, H315, H319, H335

References & Citations

[1]Bill Severson, et al. Anti-viral treatment and assay to screen for anti-viral agent. WO 2011097607 A1|[2]Sarah A Comerford, et al. Acetate dependence of tumors. Cell. 2014 Dec 18;159 (7) :1591-602.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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