Ac-CoA Synthase Inhibitor1
Ac-CoA Synthase Inhibitor1 is a potent, reversible acetate-dependent acetyl-CoA synthetase 2 (ACSS2) inhibitor with an IC50 of 0.6 μM[1]. Ac-CoA Synthase Inhibitor1 inhibits the respiratory syncytial virus (RSV) [2].
Product Specifications
CAS Number
[508186-14-9]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
RSV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection; Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/Ac-CoA_Synthase_Inhibitor1.html
Purity
99.70
Solubility
DMSO : 31.25 mg/mL (ultrasonic)
Smiles
O=C(NCCOC)NC1=CC=C2N=C(C3=CC=CS3)C(C4=CC=CS4)=NC2=C1
Molecular Formula
C20H18N4O2S2
Molecular Weight
410.51
Precautions
H302, H315, H319, H335
References & Citations
[1]Bill Severson, et al. Anti-viral treatment and assay to screen for anti-viral agent. WO 2011097607 A1|[2]Sarah A Comerford, et al. Acetate dependence of tumors. Cell. 2014 Dec 18;159 (7) :1591-602.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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