Nicotredole
Nicotredole (Tryptamide) is an orally active anti-inflammatory and analgesic agent. Nicotredole exhibits evident antiinflammatory effects of potency comparable with Phenylbutazone. Nicotredole has only weak ulcerogenic activity[1][2][3].
Product Specifications
CAS Number
[29876-14-0]
Product Name Alternative
Tryptamide
UNSPSC
12352005
Hazard Statement
H315, H319, H320
Target
Others
Type
Reference compound
Related Pathways
Others
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/nicotredole.html
Concentration
10mM
Purity
99.87
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
O=C(C1=CC=CN=C1)NCCC2=CNC3=C2C=CC=C3
Molecular Formula
C16H15N3O
Molecular Weight
265.31
Precautions
H315, H319, H320
References & Citations
[1]Herman ZS, et, al. Basic pharmacological properties of a novel antiinflammatory drug tryptamide. Pol J Pharmacol Pharm. Nov-Dec 1987;39 (6) :729-36.|[2]Szumiło H. Pharmacokinetics of tryptamide following oral and intraperitoneal administration in rats. Acta Pol Pharm. 1990;47 (1-2) :19-22.|[3]Kulig D, et, al. A comparison of anti-inflammatory, analgesic and ulcerogenic action of tryptamide, ibuprofen and piroxicam. Pol J Pharmacol Pharm. Nov-Dec 1987;39 (6) :769-72.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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