DMT-2'O-MOE-rG (ib) Phosphoramidite

DMT-2'O-MOE-rG (ib) Phosphoramidite belongs to cyanoethyl-protected nucleoside phosphoramidites. DMT-2'O-MOE-rG (ib) Phosphoramidite is a derivative of nucleotide and guanosine. DMT-2'O-MOE-rG (ib) Phosphoramidite can be used for the stereochemical synthesis of phosphorothioate oligonucleotides[1].

Product Specifications

CAS Number

[251647-55-9]

UNSPSC

12352005

Hazard Statement

H315, H319

Target

DNA/RNA Synthesis; Nucleoside Antimetabolite/Analog

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/dmt-2-o-moe-rg-ib-phosphoramidite.html

Purity

95.01

Solubility

DMSO : 200 mg/mL (ultrasonic)

Smiles

COCCO[C@@H]1[C@H](OP(N(C(C)C)C(C)C)OCCC#N)[C@@H](COC(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)C4=CC=C(OC)C=C4)O[C@H]1N5C=NC6=C5N=C(NC6=O)NC(C(C)C)=O

Molecular Formula

C47H60N7O10P

Molecular Weight

913.99

Precautions

H315, H319

References & Citations

[1]Vasulinga T, et al. Stereoselective Synthesis of Alkylphosphonates: A Facile Rearrangement of Cyanoethyl-Protected Nucleoside Phosphoramidites. Org. Proc. Res. Dev. 2004, 8, 4, 603–608