GLP-1 receptor agonist 10

GLP-1 receptor agonist 10 (compound 42) is an agonist of GLP Receptor. GLP-1 receptor agonist 10 inhibits food intake and reduces glucose excursion in mice. GLP-1 receptor agonist 10 can be used in the study of type 2 diabetes (T2DM) and obesity[1].

Product Specifications

CAS Number

[3015555-46-8]

UNSPSC

12352005

Target

GLP Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/glp-1-receptor-agonist-10.html

Concentration

10mM

Purity

99.51

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

FC(F)(F)C1=CC=C(COC2=CC=CC(N3C=NN(CC4=NC(C(F)=CC(C(O)=O)=C5)=C5N4C[C@@H]6CCO6)CC3)=N2)C(OC)=C1

Molecular Formula

C30H28F4N6O5

Molecular Weight

628.57

References & Citations

[1]Chen L, et al. Discovery of Novel 5,6-Dihydro-1,2,4-triazine Derivatives as Efficacious Glucagon-Like Peptide-1 Receptor Agonists. J Med Chem. 2023 Jun 22;66 (12) :7988-8010.