Cortistatin (Rat)

<strong>Cortistatin (Rat)</strong> <strong>Catalog number:</strong> MDP0696 <strong>CAS Number: </strong>N/A <strong>Sequence: </strong>Pro-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Ser-Ser-Cys-Lys (Disulfide bond between Cys2-Cys13) <strong>Amount:</strong> 500 ug <strong>Molecular Weight:</strong> 1720.8 g/mol <strong>Supplied as:</strong> Powder <strong>Applications:</strong> molecular tool for various biochemical applications <strong>Storage:</strong> -20 °C <strong>WARNING:</strong> For in vitro Research Use Only. NOT for use on humans or animals. <strong>Grade:</strong> Biotechnology grade. All products are highly pure. <strong>References:</strong> 1: Zhao Y, Qiu C, Wang W, Peng J, Cheng X, Shangguan Y, Xu M, Li J, Qu R, Chen X, Jia S, Luo D, Liu L, Li P, Guo F, Vasilev K, Liu L, Hayball J, Dong S, Pan X, Li Y, Guo L, Cheng L, Li W. Cortistatin protects against intervertebral disc degeneration through targeting mitochondrial ROS-dependent NLRP3 inflammasome activation Theranostics. 2020 May 27;10(15):7015-7033. 2: Balbaba M, Dal A, Çolakoğlu N, Bulmuş Ö, Ulaş F, Yıldırım H, Aydemir O, Eröksüz Y. Anti-inflammatory effect of cortistatin in rat endotoxin-induced uveitis model Indian J Ophthalmol. 2020 Sep;68(9):1920-1924. 3: Connor M, Ingram SL, Christie MJ. Cortistatin increase of a potassium conductance in rat locus coeruleus in vitro Br J Pharmacol. 1997 Dec;122(8):1567-72. 4: Baranowska B, Bik W, Baranowska-Bik A, Wolinska-Witort E, Chmielowska M, Martynska L. Cortistatin and pituitary hormone secretion in rat J Physiol Pharmacol. 2009 Mar;60(1):151-6. 5: Phillips JK. Cortistatin-can it or can it not prevent vascular calcification by modulation of Wnt signalling? Acta Physiol (Oxf). 2018 Jul;223(3):e13089. 6: Spier AD, de Lecea L. Cortistatin: a member of the somatostatin neuropeptide family with distinct physiological functions Brain Res Brain Res Rev. 2000 Sep;33(2-3):228-41. 7: Deghenghi R, Avallone R, Torsello A, Muccioli G, Ghigo E, Locatelli V. Growth hormone-inhibiting activity of cortistatin in the rat J Endocrinol Invest. 2001 Dec;24(11):RC31-3. 8: Chiu CT, Wen LL, Pao HP, Wang JY. Cortistatin is induced in brain tissue and exerts neuroprotection in a rat model of bacterial meningoencephalitis J Infect Dis. 2011 Nov 15;204(10):1563-72. 9: Rubinfeld H, Shimon I. Cortistatin - a new neuroendocrine hormone? Pediatr Endocrinol Rev. 2006 Dec-2007 Jan;4(2):106-10. <a href="https://pubmed.ncbi.nlm.nih.gov/29863267">10: Geng L, Wang XT, Yu J, Yang YL. Antagonism of cortistatin against cyclosporine-induced apoptosis in rat myocardial cells and its effect on myocardial apoptosis gene expression Eur Rev Med Pharmacol Sci. 2018 May;22(10):3207-3213. </a> <br><strong>Products Related to Cortistatin (Rat) can be found at</strong> <a href="https://moleculardepot.com/product-category/Peptides/"> Peptides</a>