α-Glucosidase-IN-22

α-Glucosidase-IN-22 (compound 7i), a benzimidazole, is a potent α-glucosidase inhibitor with an IC50 of 0.64 μM. α-Glucosidase-IN-22 is a potent anti-diabetic agent and has the potential for type 2 diabetes mellitus (T2DM) research[1].

Product Specifications

CAS Number

[2870693-28-8]

UNSPSC

12352005

Hazard Statement

H302-H315-H319

Target

Glycosidase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/α-glucosidase-in-22.html

Purity

99.13

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

S=C1NC2=CC=C(C=C2N1)/N=C/C3=CC=C(C=C3O)O

Molecular Formula

C14H11N3O2S

Molecular Weight

285.32

Precautions

P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501

References & Citations

[1]Sardar Ali, et al. Novel 5- (Arylideneamino) -1 H-Benzo[ d]imidazole-2-thiols as Potent Anti-Diabetic Agents: Synthesis, In Vitro α-Glucosidase Inhibition, and Molecular Docking Studies. ACS Omega. 2022 Nov 23;7 (48) :43468-43479.