α-Glucosidase-IN-22
Product Specifications
UNSPSC Description
α-Glucosidase-IN-22 (compound 7i), a benzimidazole, is a potent α-glucosidase inhibitor with an IC50 of 0.64 μM. α-Glucosidase-IN-22 is a potent anti-diabetic agent and has the potential for type 2 diabetes mellitus (T2DM) research[1].
Target Antigen
Glycosidase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/α-glucosidase-in-22.html
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
S=C1NC2=CC=C(C=C2N1)/N=C/C3=CC=C(C=C3O)O
Molecular Weight
285.32
References & Citations
[1]Sardar Ali, et al. Novel 5-(Arylideneamino)-1 H-Benzo[ d]imidazole-2-thiols as Potent Anti-Diabetic Agents: Synthesis, In Vitro α-Glucosidase Inhibition, and Molecular Docking Studies. ACS Omega. 2022 Nov 23;7(48):43468-43479.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-152158/α-Glucosidase-IN-22-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-152158/α-Glucosidase-IN-22-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2870693-28-8
Available Sizes
Curated Selection
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