α-Glucosidase-IN-22

α-Glucosidase-IN-22 (compound 7i), a benzimidazole, is a potent α-glucosidase inhibitor with an IC50 of 0.64 μM. α-Glucosidase-IN-22 is a potent anti-diabetic agent and has the potential for type 2 diabetes mellitus (T2DM) research[1].

Product Specifications

CAS Number

[2870693-28-8]

UNSPSC

12352005

Hazard Statement

H302-H315-H319

Target

Glycosidase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/α-glucosidase-in-22.html

Purity

99.13

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

S=C1NC2=CC=C(C=C2N1)/N=C/C3=CC=C(C=C3O)O

Molecular Formula

C14H11N3O2S

Molecular Weight

285.32

Precautions

P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501

References & Citations

[1]Sardar Ali, et al. Novel 5- (Arylideneamino) -1 H-Benzo[ d]imidazole-2-thiols as Potent Anti-Diabetic Agents: Synthesis, In Vitro α-Glucosidase Inhibition, and Molecular Docking Studies. ACS Omega. 2022 Nov 23;7 (48) :43468-43479.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

62560151 3x 1.0 µg DNA

NCRNA00159 CRISPR All-in-one AAV vector set (with saCas9)(Human)

Ask

View Details

GA218249 1 Kit

Mouse Ighv6-5 activation kit by CRISPRa

Ask

View Details

MR211149 10 µg

Snd1 (NM_019776) Mouse Tagged ORF Clone

Ask

View Details

GR111103-2 2x 96 Well

Nori® Human HSP90 ELISA Kit- 2 Plates

Ask

View Details