NP-G2-044

NP-G2-044 is a potent, orally active fascin inhibitor, with an IC50 of ~2 μM. NP-G2-044 blocks tumor metastasis and increases antitumor immune response[1][2].

Product Specifications

CAS Number

[1807454-59-6]

UNSPSC

12352005

Hazard Statement

H302, H315, H319

Target

β-catenin

Type

Reference compound

Related Pathways

Stem Cell/Wnt

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/np-g2-044.html

Purity

99.75

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(C1=C(C)OC=C1)NC2=NN(CC3=CC=C(C(F)(F)F)C=C3)C4=C2C=CC=C4

Molecular Formula

C21H16F3N3O2

Molecular Weight

399.37

Precautions

H302, H315, H319

References & Citations

[1]Han S, et al. Improving fascin inhibitors to block tumor cell migration and metastasis. Mol Oncol. 2016;10 (7) :966-980.|[2]Vincent Chung, et al. Abstract C053: NP-G2-044, a novel fascin inhibitor, blocks tumor metastasis and increases antitumor immune response.|[3]Fascin Inhibitor NP-G2-044.