Senecionine N-oxide-d3

Senecionine N-oxide-d3 is the deuterium labeled Senecionine N-oxide. Senecionine n-oxide is the primary product of pyrrolizidine alkaloid biosynthesis in root cultures of Senecio vulgaris. Senecionine N-oxide has anti-cancer activity[1][2].

Product Specifications

UNSPSC

12352005

Target

Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Others

Field of Research

Cancer

Purity

95.45

Solubility

10 mM in DMSO

Smiles

O=C(O[C@]1([H])CC[N+]2([O-])[C@]1([H])C(COC([C@@](O)(C([2H])([2H])[2H])[C@H](C)C/3)=O)=CC2)C3=C/C

Molecular Formula

C18H22D3NO6

Molecular Weight

354.41

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Thomas Hartmann, et al. Senecionine n-oxide, the primary product of pyrrolizidine alkaloid biosynthesis in root cultures of Senecio vulgaris. Phytochemistry, Volume 26, Issue 6, 1987, Pages 1639-1643|[3]Kupchan SM, et al. Tumor inhibitors. XXII. Senecionine and senecionine N-oxide, the active principles of Senecio triangularis. J Pharm Sci. 1967 Apr;56 (4) :541-3.