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N6-Bz-5'-O-DMTr-3'-deoxyadenosine-2'-O-CED-phosphoramidite

Product Specifications

UNSPSC Description

N6-Bz-5'-O-DMTr-3'-deoxyadenosine-2'-O-CED-phosphoramidite is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].

Target Antigen

Nucleoside Antimetabolite/Analog

Type

Oligonucleotides

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/n6-bz-5-o-dmtr-3-deoxyadenosine-2-o-ced-phosphoramidite.html

Solubility

10 mM in DMSO

Smiles

CC(C)N(C(C)C)P(O[C@@H]1C[C@@H](COC(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)C4=CC=C(OC)C=C4)O[C@H]1N(C=N5)C6=C5C(NC(C7=CC=CC=C7)=O)=NC=N6)OCCC#N

Molecular Weight

857.93

References & Citations

[1]Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-W545104/N6-Bz-5-O-DMTr-3-deoxyadenosine-2-O-CED-phosphoramidite-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-W545104/

Clinical Information

No Development Reported

CAS Number

207347-42-0

Available Sizes

Curated Selection

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