N6-Bz-5'-O-DMTr-3'-deoxyadenosine-2'-O-CED-phosphoramidite
N6-Bz-5'-O-DMTr-3'-deoxyadenosine-2'-O-CED-phosphoramidite is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) [1].
Product Specifications
CAS Number
[207347-42-0]
UNSPSC
12352005
Hazard Statement
H302-H315-H319
Target
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/n6-bz-5-o-dmtr-3-deoxyadenosine-2-o-ced-phosphoramidite.html
Solubility
10 mM in DMSO
Smiles
CC(C)N(C(C)C)P(O[C@@H]1C[C@@H](COC(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)C4=CC=C(OC)C=C4)O[C@H]1N(C=N5)C6=C5C(NC(C7=CC=CC=C7)=O)=NC=N6)OCCC#N
Molecular Formula
C47H52N7O7P
Molecular Weight
857.93
Precautions
P264-P270-P280-P302+P352-P330-P362+P364-P501
References & Citations
[1]Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26 (6) :1490-1500.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
Available Sizes
Explore Other Products
Browse additional items from our catalog
Zkscan14 Mouse shRNA Lentiviral Particle (Locus ID 67235)
Rabbit Monoclonal GFAP Antibody (GFAP/8616R) [DyLight 488]
![Recombinant Human CD147 Protein (aa 1-205) [Fc]](https://cdn.genprice.uk/genprice/uk/genprice2.webp)
Recombinant Human CD147 Protein (aa 1-205) [Fc]
Monoclonal MMRN1 Antibody (monoclonal) (M02), Clone: 4B9