CD73-IN-18

CD73-IN-18 (compound 35j) is an orally available inhibitor of extracellular 5-nucleotidase (CD73) . CD73-IN-18 can be used in anti-cancer research[1].

Product Specifications

CAS Number

[3037968-61-6]

UNSPSC

12352005

Target

CD73

Type

Reference compound

Related Pathways

Immunology/Inflammation

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/cd73-in-18.html

Smiles

O=C(C(C1=CC(NCCC2=CC=CC=C2)=C(N=N1)C3=COC=C3)=CN4)NC4=O

Molecular Formula

C20H17N5O3

Molecular Weight

375.38

References & Citations

[1]Xu Y, et al. Discovery of Novel 5- (Pyridazin-3-yl) pyrimidine-2,4 (1H,3H) -dione Derivatives as Potent and Orally Bioavailable Inhibitors Targeting Ecto-5'-nucleotidase. J Med Chem. 2024 Oct 10.