Human CK1 ε Protein Active

<strong>Human CK1 Œµ Protein Active</strong>_x000D_ <strong>Catalog number:</strong> B2014033_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 10 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 72 kDa_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> ‚àí20¬∞C_x000D_ <strong>Keywords:</strong> CK1 Œµ, active, GST tagged human_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MŒ©-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Janovsk P, Normant E, Miskin H, Bryja V. Targeting Casein Kinase 1 (CK1) in Hematological Cancers Int J Mol Sci. 2020 Nov 27;21(23):9026._x000D_ 2: Zhao B, Li L, Tumaneng K, Wang CY, Guan KL. A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP) Genes Dev. 2010 Jan 1;24(1):72-85._x000D_ 3: Francisco JC, Virshup DM. Casein Kinase 1 and Human Disease: Insights From the Circadian Phosphoswitch Front Mol Biosci. 2022 Jun 3;9:911764._x000D_ 4: Catarzi D, Varano F, Vigiani E, Lambertucci C, Spinaci A, Volpini R, Colotta V. Casein Kinase 1 Inhibitors as Promising Therapeutic Agents for Neurodegenerative Disorders Curr Med Chem. 2022;29(27):4698-4737._x000D_ 5: Knippschild U, Wolff S, Giamas G, Brockschmidt C, Wittau M, W_rl PU, Eismann T, Stter M. The role of the casein kinase 1 (CK1) family in different signaling pathways linked to cancer development Onkologie. 2005 Oct;28(10):508-14._x000D_ 6: Akizuki K, Toyama T, Yamashita M, Sugiyama Y, Ishida A, Kameshita I, Sueyoshi N. Facile preparation of highly active casein kinase 1 using Escherichia coli constitutively expressing lambda phosphatase Anal Biochem. 2018 May 15;549:99-106._x000D_ 7: Reinhardt J, Ferandin Y, Meijer L. Purification of CK1 by affinity chromatography on immobilised axin Protein Expr Purif. 2007 Jul;54(1):101-9._x000D_ 8: Fulcher LJ, Bozatzi P, Tachie-Menson T, Wu KZL, Cummins TD, Bufton JC, Pinkas DM, Dunbar K, Shrestha S, Wood NT, Weidlich S, Macartney TJ, Varghese J, Gourlay R, Campbell DG, Dingwell KS, Smith JC, Bullock AN, Sapkota GP. The DUF1669 domain of FAM83 family proteins anchor casein kinase 1 isoforms Sci Signal. 2018 May 22;11(531):eaao2341._x000D_ 9: Top D, O'Neil JL, Merz GE, Dusad K, Crane BR, Young MW. CK1/Doubletime activity delays transcription activation in the circadian clock Elife. 2018 Apr 3;7:e32679._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/27488834">10: Sinnberg T, Wang J, Sauer B, Schittek B. Casein kinase 1 has a non-redundant and dominant role within the CK1 family in melanoma progression BMC Cancer. 2016 Aug 3;16:594. </a>_x000D_ _x000D_ <strong>Products Related to Human CK1 Œµ Protein Active can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>