N-Methylbenzamide

N-Methylbenzamide is a potent phosphodiesterase 10A (PDE10A) inhibitor. N-Methylbenzamide has anti-cancer activity[1][2].

Product Specifications

CAS Number

[613-93-4]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Phosphodiesterase (PDE)

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/n-methylbenzamide.html

Purity

99.93

Solubility

DMSO : ≥ 200 mg/mL

Smiles

O=C(NC)C1=CC=CC=C1

Molecular Formula

C8H9NO

Molecular Weight

135.17

Precautions

H302, H315, H319, H335

References & Citations

[1]Kilburn JP, et al. N-Methylanilide and N-methylbenzamide derivatives as phosphodiesterase 10A (PDE10A) inhibitors. Bioorg Med Chem. 2013 Oct 1;21 (19) :6053-62.|[2]Gate, E. N., et al. Structural studies on bioactive compounds. 4. A structure-antitumor activity study on analogs of N-methylformamide. Journal of Medicinal Chemistry, 1986, 29 (6), 1046–1052.