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PGD2-IN-1

PGD2-IN-1 is an antagonist of DP extracted from patent WO 2006044732 A2, example 15 (d) ; has an IC50 of 0.3 nM.

Product Specifications

CAS Number

885066-67-1

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

Prostaglandin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/PGD2-IN-1.html

Concentration

10mM

Purity

98.24

Solubility

DMSO : 25 mg/mL (ultrasonic)

Smiles

O=C(O)C(C)(C)C1=CC=CC(C2=NC(OC)=NC(NCCC3=CC=C(Cl)C=C3Cl)=C2)=C1

Molecular Formula

C23H23Cl2N3O3

Molecular Weight

460.35

Precautions

H315, H319, H335

References & Citations

[1]Lim, Sungtaek, et al. 2, 6-SUBSTITUTED-4-MONOSUBSTITUTEDAMINO-PYRIMIDINE AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS. WO2006044732A2.|[2]Mu L, et al. Understanding DP receptor antagonism using a CoMSIA approach. Bioorg Med Chem Lett. 2011 Jan 1;21 (1) :66-75.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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