Ent- (+) -Verticilide
Ent- (+) -verticilide is a potent and selective inhibitor of cardiac ryanodine receptor (RyR2) calcium release channels with antiarrhythmic activity. ent- (+) -verticilide inhibits RyR2-mediated diastolic Ca2+ leak and exhibits higher potency and a distinct mechanism of action compared with theDantrolene and Tetracaine. ent- (+) -verticilide is a useful tool to investigate the therapeutic potential of targeting RyR2 hyperactivity in heart and brain pathologies[1].
Product Specifications
CAS Number
2056011-05-1
UNSPSC
12352005
Target
Calcium Channel
Type
Peptides
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ent-plus-verticilide.html
Purity
99.91
Solubility
10 mM in DMSO
Smiles
CCCCC[C@H]1C(N([C@@H](C(O[C@H](C(N([C@@H](C(O[C@H](C(N([C@@H](C(O[C@H](C(N([C@@H](C(O1)=O)C)C)=O)CCCCC)=O)C)C)=O)CCCCC)=O)C)C)=O)CCCCC)=O)C)C)=O
Molecular Formula
C44H76N4O12
Molecular Weight
853.09
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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