MSX-122
MSX-122 is an orally active partial antagonist of CXCR4, inhibiting CXCR4/CXCL12 actions, with an IC50 of ～10 nM. MSX-122 has anti-inflammatory and anti-metastatic activity.
Product Specifications
CAS Number
[897657-95-3]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
CXCR
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer; Inflammation/Immunology; Endocrinology
Assay Protocol
https://www.medchemexpress.com/MSX-122.html
Purity
98.16
Solubility
DMSO : 4 mg/mL (ultrasonic)
Smiles
C1(CNC2=NC=CC=N2)=CC=C(CNC3=NC=CC=N3)C=C1
Molecular Formula
C16H16N6
Molecular Weight
292.34
Precautions
H302, H315, H319, H335
References & Citations
[1]Liang Z, et al. Development of a unique small molecule modulator of CXCR4. PLoS One. 2012;7 (4) :e34038.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 1
Isoform
CXCR4
Available Sizes
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