7α-Thiospironolactone

7α-Thiospironolactone is the transformation product of spironolactone (HY-B0561), which can be obtained by the metabolism of Thermomyces lanuginosus[1].

Product Specifications

CAS Number

[38753-76-3]

Product Name Alternative

Deacetylspironolactone; Mercaptospironolactone

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Drug Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/7α-thiospironolactone.html

Purity

99.85

Solubility

DMSO : 12.5 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

C[C@@]12[C@@]3(OC(CC3)=O)CC[C@@]1([H])[C@@]4([H])[C@]([C@@]5(C(C[C@H]4S)=CC(CC5)=O)C)([H])CC2

Molecular Formula

C22H30O3S

Molecular Weight

374.54

Precautions

H302, H315, H319, H335

References & Citations

[1]B S, et al. Microbial synthesis of mammalian metabolites of spironolactone by thermophilic fungus Thermomyces lanuginosus. Steroids. 2018 Aug;136:1-7.