SPSB2-iNOS inhibitory cyclic peptide-2
SPSB2-iNOS inhibitory cyclic peptide-2 (Compound CP2) is an inhibitor for the interaction of SPRY domain and SOCS-box protein 2 (SPSB2) and iNOS, through binding SPSB2 on iNOS site with KD of 21 nM. SPSB2-iNOS inhibitory cyclic peptide-2 is reduction-resistant and oxidatively stable[1].
Product Specifications
CAS Number
1989528-33-7
UNSPSC
12352209
Target
NO Synthase
Type
Peptides
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/spsb2-inos-inhibitory-cyclic-peptide-2.html
Solubility
10 mM in DMSO
Smiles
O=C(N[C@H](C(N[C@@](C(N[C@H](C(N[C@H](C(N[C@H](C(NCCC(N1)=O)=O)CC(N)=O)=O)CC(N)=O)=O)CC(N)=O)=O)([H])[C@@H](C)CC)=O)CC(O)=O)[C@@H]1CC2=CNC3=CC=CC=C23
Molecular Formula
C36H49N11O12
Molecular Weight
827.84
References & Citations
[1]Yap BK, et al., Redox-stable cyclic peptide inhibitors of the SPSB2-iNOS interaction. FEBS Lett. 2016 Mar;590 (6) :696-704.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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