4-Bromobenzoic acid

4-Bromobenzoic acid is a tyrosinase inhibitor (IC50 range 0-0.3 mg/mL) . 4-Bromobenzoic acid can be metabolized through the protocatechuic acid (PCA) pathway. 4-Bromobenzoic acid can be used for research on cosmetic whitening or pigmentation conditions[1][2].

Product Specifications

CAS Number

[586-76-5]

UNSPSC

12352200

Hazard Statement

H302, H402

Target

Tyrosinase

Type

Biochemical Assay Reagents

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/4-bromobenzoic-acid.html

Purity

99.85

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

BrC1=CC=C(C(O)=O)C=C1

Molecular Formula

C7H5BrO2

Molecular Weight

201.02

Precautions

H302, H402

References & Citations

[1]4-Bromobenzoic acid|[2]Nicolson GL, Singer SJ. Ferritin-conjugated plant agglutinins as specific saccharide stains for electron microscopy: application to saccharides bound to cell membranes. Proc Natl Acad Sci U S A. 1971 May;68 (5) :942-5.|[3]Adebusoye SA. Biological degradation of 4-chlorobenzoic acid by a PCB-metabolizing bacterium through a pathway not involving (chloro) catechol. Biodegradation. 2017 Feb;28 (1) :37-51.|[4]Alam F, et al. Investigating the Tyrosinase Inhibitory Activity of 4‐Bromobenzoic Acid Hydrazone‐Schiff Bases: In Vitro, Molecular Structure and Docking Studies[J]. ChemistrySelect, 2024, 9 (44) : e202401987.