(S) -6-O-Desmethylnaproxen

(S) -6-O-Desmethylnaproxen ((S) -6-Desmethyl Naproxen) is a metabolite of the non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor (+) -naproxen ((S) -naproxen) . (S) -6-O-Desmethylnaproxen is formed from (S) -naproxen by the cytochrome P450 (CYP) isoforms CYP1A2 and CYP2C9.

Product Specifications

CAS Number

[52079-10-4]

Product Name Alternative

(S) -6-Desmethyl Naproxen

UNSPSC

12352005

Hazard Statement

H302, H317, H372, H400

Target

COX

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/s-6-o-desmethylnaproxen.html

Purity

95.73

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

OC([C@H](C1=CC2=C(C=C(C=C2)O)C=C1)C)=O

Molecular Formula

C13H12O3

Molecular Weight

216.23

Precautions

H302, H317, H372, H400

References & Citations

[1]Miners, et al. Cytochromes P450, 1A2, and 2C9 are responsible for the human hepatic O-demethylation of R- and S-naproxen. Biochem. Pharmacol. 51 (8), 1003-1008 (1996) .