L-Homocysteine
Product Specifications
UNSPSC Description
L-Homocysteine, an amino acid, is a homocysteine that has L configuration. Homocysteine is an essential intermediate in normal mammalian metabolism of methionine. L-Homocysteine induces upregulation of Cathepsin V that mediates vascular endothelial inflammation in hyperhomocysteinaemia[1][2].
Target Antigen
Cathepsin; Endogenous Metabolite
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/l-homocysteine.html
Purity
98.0
Solubility
DMSO : < 1 mg/mL|H2O : 25 mg/mL (ultrasonic)
Smiles
N[C@@H](CCS)C(O)=O
Molecular Weight
135.188
References & Citations
[1]Finkelstein JD, et al. Homocysteine. Int J Biochem Cell Biol. 2000 Apr;32(4):385-9.|[2]Leng YP, et al. l-Homocysteine-induced cathepsin V mediates the vascular endothelial inflammation in hyperhomocysteinaemia. Br J Pharmacol. 2018 Apr;175(8):1157-1172.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light, stored under nitrogen)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-W010347/L-Homocysteine-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-W010347/L-Homocysteine-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
6027-13-0
Available Sizes
Curated Selection
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