Lanabecestat (camsylate)
Lanabecestat camsylate is a potent, orally active and blood-brain barrier penetrating BACE1 inhibitor with a Ki of 0.4 nM. Lanabecestat camsylate is used for the research of Alzheimer's disease[1].
Product Specifications
CAS Number
1522418-41-2
Product Name Alternative
LY3314814 (camsylate) ; AZD3293 (camsylate)
UNSPSC
12352005
Target
Beta-secretase
Type
Reference compound
Related Pathways
Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/lanabecestat-camsylate.html
Smiles
CC#CC1=CC(C2=CC([C@@]34N=C(C)C(N)=N4)=C(C[C@@]53CC[C@@H](OC)CC5)C=C2)=CN=C1.O=S(C[C@@]6(C7(C)C)C(C[C@H]7CC6)=O)(O)=O
Molecular Formula
C36H44N4O5S
Molecular Weight
644.82
References & Citations
[1]Eketjäll S, et al. AZD3293: A Novel, Orally Active BACE1 Inhibitor with High Potency and Permeability and Markedly Slow Off-Rate Kinetics. J Alzheimers Dis. 2016;50 (4) :1109-23.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 3
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC470525-100 1x 100 µL
CD63 (MX-49.129.5), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC400630-500 1x 500 µL
Mucin 1 / EMA / Episialin / CD227 (VU-2G7), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC880012-500 1x 500 µL
Tyrosinase (T311), CF488A conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC882960-500 1x 500 µL
Desmin (Muscle Cell Marker) (DES/2960R), CF488A conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC680784-500 1x 500 µL
CD56 / NCAM (NCAM1/784), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC680918-100 1x 100 µL
CD44 Standard (HCAM/918), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details