Necrocide 1
Product Specifications
UNSPSC Description
Necrocide 1 (compound (S)-38) a potent anticancer agent. Necrocide 1 has antiproliferative activity with an IC50 value of 0.48 and 2 nM for MCF-7 and PC3, respectively[1].
Target Antigen
Others
Type
Reference compound
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/necrocide-1.html
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1NC2=C(C=CC(OC)=C2C)[C@]1(C3CCCCCC3)C4=CC=C(O)C=C4
Molecular Weight
365.47
References & Citations
[1]Synthesis and Antitumor Effect in Vitro and in Vivo of Substituted 1,3-Dihydroindole-2-ones
J. Med. Chem., Article ASAP
DOI: 10.1021/jm100763j
Publication Date (Web): September 16, 2010|[2]Christensen MK, et, al. Synthesis and antitumor effect in vitro and in vivo of substituted 1,3-dihydroindole-2-ones. J Med Chem. 2010 Oct 14;53(19):7140-5.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-14307/Necrocide-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-14307/Necrocide-1-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1247028-61-0
Available Sizes
Curated Selection
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