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O-Propargyl-Puromycin

Product Specifications

UNSPSC Description

O-Propargyl-Puromycin, an alkyne analog of puromycin, is a potent protein synthesis inhibitor. O-Propargyl-Puromycin is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Target Antigen

Biochemical Assay Reagents

Type

Reference compound

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/O-Propargyl-Puromycin.html

Solubility

DMSO : ≥ 31 mg/mL|H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C)

Smiles

CN(C)C1=C2C(N([C@H]3[C@H](O)[C@H](NC([C@@H](N)CC4=CC=C(OCC#C)C=C4)=O)[C@@H](CO)O3)C=N2)=NC=N1

Molecular Weight

495.53

References & Citations

[1]Liu J, et al. Imaging protein synthesis in cells and tissues with an alkyne analog of puromycin. Proc Natl Acad Sci U S A. 2012 Jan 10;109(2):413-8.

Shipping Conditions

Room Temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-15680/O-Propargyl-Puromycin-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-15680/O-Propargyl-Puromycin-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

1416561-90-4

Available Sizes

Curated Selection

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