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Negamycin

Negamycin is a compound with antibacterial activity that inhibits protein synthesis by binding to the head domain of the bacterial ribosomal small subunit, leading to cell death, and also promotes misreading of near-cognate codons.

Product Specifications

CAS Number

[33404-78-3]

UNSPSC

12352211

Target

Bacterial

Type

Natural Products

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/negamycin.html

Smiles

NC[C@H](O)C[C@@H](N)CC(NN(C)CC(O)=O)=O

Molecular Formula

C9H20N4O4

Molecular Weight

248.28

References & Citations

[1]Negamycin induces translational stalling and miscoding by binding to the small subunit head domain of the Escherichia coli ribosome

Shipping Conditions

Room temperature

Scientific Category

Natural Products

Clinical Information

No Development Reported

Curated Selection

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