Diatrizoic acid
Diatrizoic acid (Diatrizoate) is an iodinated radiocontrast agent and has the potential for radiographic imaging of the airways. Diatrizoic acid induces mitochondrial turnover and oxidative stress, and activating apoptosis by dysregulating calcium[1][2].
Product Specifications
CAS Number
[117-96-4]
Product Name Alternative
Diatrizoate; Amidotrizoic acid
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
Neuroscience-Neuromodulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/Diatrizoic-acid.html
Purity
98.33
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(O)C1=C(I)C(NC(C)=O)=C(I)C(NC(C)=O)=C1I
Molecular Formula
C11H9I3N2O4
Molecular Weight
613.91
Precautions
H302, H315, H319, H335
References & Citations
[1]El-Gendy N, et al. Dry powdered aerosols of diatrizoic acid nanoparticle agglomerates as a lung contrast agent. Int J Pharm. 2010 May 31;391 (1-2) :305-12.|[2]Dakota B Ward, et al. Radiocontrast Agent Diatrizoic Acid Induces Mitophagy and Oxidative Stress via Calcium Dysregulation. Int J Mol Sci. 2019 Aug 21;20 (17) :4074.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Available Sizes
Curated Selection
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