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Recombinant Human High affinity immunoglobulin epsilon receptor subunit gamma (FCER1G), partial

Product Specifications

Product Name Alternative

Fc receptor gamma-chain ; FcRgammaFc-epsilon RI-gammaIgE Fc receptor subunit gamma ; FceRI gamma

Abbreviation

Recombinant Human FCER1G protein, partial

Gene Name

FCER1G

UniProt

P30273

Expression Region

45-86aa

Organism

Homo sapiens (Human)

Target Sequence

RLKIQVRKAAITSYEKSDGVYTGLSTRNQETYETLKHEKPPQ

Tag

N-terminal 6xHis-tagged

Type

Developed Protein

Source

Yeast

Field of Research

Immunology

Relevance

Associates with a variety of FcR alpha chains to form a functional signaling complex. Regulates several aspects of the immune response. The gamma subunit has a critical role in allowing the IgE Fc receptor to reach the cell surface. Also involved in collagen-mediated platelet activation and in neutrophil activation mediated by integrin.

Endotoxin

Not test

Purity

Greater than 90% as determined by SDS-PAGE.

Activity

Not Test

Form

Liquid or Lyophilized powder

Buffer

If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Function

Associates with a variety of FcR alpha chains to form a functional signaling complex. Regulates several aspects of the immune response. The gamma subunit has a critical role in allowing the IgE Fc receptor to reach the cell surface. Also involved in collagen-mediated platelet activation and in neutrophil activation mediated by integrin.

Molecular Weight

6.9 kDa

References & Citations

Characterization and expression of the gene for the human Fc receptor gamma subunit. Definition of a new gene family.Kuester H., Thompson H., Kinet J.-P.J. Biol. Chem. 265:6448-6452 (1990)

Storage Conditions

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Protein Length

Cytoplasmic Domain

Available Sizes

Curated Selection

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